Agnieszka Staśkiewicz

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Born: February 11, 1994, Żagań, Poland

Hobby: traveling, swimming

Address:

Department of Bioorganic Chemistry,

Faculty of Chemistry,

Wroclaw University of Science and Technology,

Wybrzeże Wyspianskiego 27,

50-370 Wroclaw, Poland

Tel: 0048 71 320 2461, Fax: 0048 71 320 2435

e-mail: agnieszka.staskiewicz@pwr.edu.pl


Education

  • 2018 – present - PhD in Chemistry, Faculty of Chemistry, Wroclaw University of Science and Technology. Thesis title: ‘Clicked analogs for the development of druggable oxytocin analogs’. Supervisors: Prof. Rafał Latajka and Prof. Anna Maria Papini (University of Florence, Italy).
  • 2016 – 2018 - MSc in Chemistry, Faculty of Chemistry, University of Wroclaw. Thesis title: ‘The influence of the distribution of electron density around the phosphorus atom on the acidity of methylene atoms of hydrogen in the derivatives of triarylphosphoniumacetic acid’. Supervisor: PhD Alicja Kluczyk
  • 2013 – 2016 - BSc in Chemistry, Faculty of Chemistry, University of Wroclaw. Thesis title: ‘Methods of synthesis quaternary ammonium salts‘. Supervisor: Prof. Zbigniew Szewczuk


Intership

  • 10.2021 – 02.2022 - Università degli Studi di Firenze, Dipartimento di Chimica, Florence, Italy. Project: ‘Advanced techniques of synthesis and purification of peptides and proteins’ (Erasmus+)
  • 04.2021 – 08.2021 - Università degli Studi di Firenze, Dipartimento di Chimica, Florence, Italy. Project: ‘Development in peptide chemistry’ (Erasmus+)
  • 07.2020 – 08.2020 - Università degli Studi di Firenze, Dipartimento di Chimica, Florence, Italy.
  • 03.2020 – 07.2020 - Università degli Studi di Firenze, Dipartimento di Chimica, Florence, Italy. Project: ‘Professional development in the field of bioorganic chemistry’ (Erasmus+)
  • 06.2019 – 07.2019 - Università degli Studi di Firenze, Dipartimento di Chimica, Florence, Italy. Project: ‘Synthesis of clicked oxytocin analogs’ (BioTechNan)
  • 02.2018 – 06.2018 - Università degli Studi di Firenze, Dipartimento di Chimica, Florence, Italy. Project: ‘Development of a diagnostic technology based on mass spectrometry to fish out biologically relevant glycopeptides by phenylboronic-modified resin’ (Erasmus+)
  • 07.2018 – 09.2018 - Università degli Studi di Firenze, Dipartimento di Chimica, Florence, Italy. Project: ‘Development of a diagnostic technology based on mass spectrometry to fish out biologically relevant glycopeptides by phenylboronic-modified resin’ (Erasmus+)
  • 10.2016 – 06.2018 - Cooperation in a research project: ‘Optimization of the structure of phosphobetaine peptide conjugates by way of new biologically active compounds’ (The Leading National Research Center)

Professional memberships

  • Polish Chemical Society (since 2019)
  • European Chemical Society (since 2019)
  • European Peptide Society (since 2019)
  • Italian Peptide Society (since 2022)

Conference communications

Oral presentations:

  1. A. Staśkiewicz, F. Nuti, M. Jewgiński, M. Larregola, O. Lequin, C.W. Gruber, M. Chorev, P. Rovero, A.M. Papini, R. Latajka, Design, synthesis, conformational studies, and biological activity of clicked oxytocin analogues, II International Multidisciplinary Doctoral Conference of the University of Szczecin “MKDUS 2.0”, 22-24.06.2022, Szczecin, Poland
  2. A. Staśkiewicz, M. Quagliata, F. Nuti, F. Real-Fernandez, M. Jewgiński, R. Aharoni, R. Arnon, P. Rovero, A.M. Papini, R. Latajka, The role of secondary structure in series of MBP peptides for antibody recognition in Multiple Sclerosis, XVIII Ogólnopolskie Seminarium dla Doktorantów i Studentów. Na pograniczu chemii i biologii, 12-15.06.2022, Smardzewice, Poland
  3. A. Staśkiewicz, F. Nuti, M. Jewgiński, M. Larregola, O. Lequin, C.W. Gruber, M. Chorev, P. Rovero, R. Latajka, A.M. Papini, Design, synthesis, conformational studies, and biological activity of clicked oxytocin analogues, Symposium "PhD in Chemical Sciences at Unifi - PiCSU2022", 19-21.02.2022, Florence, Italy
  4. A. Staśkiewicz, L. Macchia, F. Nuti, M. Jewgiński, M. Chorev, P. Rovero, A.M. Papini, R. Latajka, Projektowanie i synteza cyklicznych analogów oksytocyny, Od teorii do eksperymentu - czyli wpływ reorganizacji wewnątrz- i międzycząsteczkowej na właściwości cząsteczek w mikro- i makroskali, 18.02.2021, Wrocław, Poland
  5. A. Staśkiewicz, L. Macchia, F. Nuti, M. Jewgiński, M. Chorev, P. Rovero, A.M. Papini, R. Latajka, Design and synthesis of clicked oxytocin analogs, IV Doctoral Forum Jan Kochanowski University, 17-19.11.2020, Kielce, Poland
  6. M. Kijewska, F. Nuti, M. Wierzbicka, M. Waliczek, P. Ledwoń, A. Staśkiewicz, T. Koch, F. Real-Fernandez, G. Sabatino, P. Rovero, P. Stefanowicz, Z. Szewczuk, A.M. Papini, The novel Boronic-ChemMatrix Resin to selectively fish out deoxyfructosylated peptides, 25th Polish Peptide Symposium, 08-12.09.2019, Wojanów, Poland.
  7. A. Staśkiewicz, M. Jewgiński, A.M. Papini, R. Latajka, Design and synthesis of [1,2,3]-triazolyl containing cyclo-nonapeptides, analogs of oxytocin, XVII Ogólnopolskie Seminarium dla Doktorantów i Studentów. Na pograniczu chemii i biologii, 12-15.05.2019, Jastrzębia Góra, Poland.
  8. A. Kluczyk, N. Zuzak, W. Pietrowicz, A. Staśkiewicz, A. Dambinova, R. Bąchor, B. Setner, M. Kijewska, P. Stefanowicz, Z. Szewczuk, Wittig reaction in peptide chemistry: application to the synthesis of peptide conjugates, 24th Polish Peptide Symposium, 03-07.09.2017, Jastrzębia Góra, Poland.

Posters:

  1. A. Staśkiewicz, M. Quagliata, F. Nuti, F. Real-Fernandez, M. Jewgiński, R. Aharoni, R. Arnon, P. Rovero, R. Latajka, A.M. Papini, The role of α-helix motif in MBP peptides for antibody recognition in Multiple Sclerosis, 36th European and 12th International Peptide Symposium, 28.08-02.09.2022, Sitges, Barcelona, Spain
  2. F. Nuti, A. Staśkiewicz, M. Larregola, B. Reztl, N. Tomasevic, M. Jewgiński, O. Lequin, C.W. Gruber, M. Chorev, P. Rovero, R. Latajka, A.M. Papini, Design, synthesis, conformational studies, and biological activity of clicked oxytocin analogues, 36th European and 12th International Peptide Symposium, 28.08‑02.09.2022, Sitges, Barcelona, Spain
  3. A. Staśkiewicz, F. Nuti, M. Jewgiński, M. Larregola, O. Lequin, C.W. Gruber, M. Chorev, P. Rovero, A.M. Papini, R. Latajka, Projektowanie, synteza, preferencje konformacyjne oraz aktywność biologiczna analogów oksytocyny, IX Łódzkie Sympozjum Doktorantów Chemii, 19-20.05.2022, Łódź, Poland
  4. A. Staśkiewicz, F. Nuti, M. Jewgiński, M. Larregola, O. Lequin, C.W. Gruber, M. Chorev, P. Rovero, A.M. Papini, R. Latajka, Projektowanie, synteza, badania konformacyjne oraz aktywność biologiczna triazolowych analogów oksytocyny, X Kongres Technologii Chemicznej, 11-14.05.2022, Wrocław, Poland
  5. A. Staśkiewicz, L. Macchia, F. Nuti, M. Jewgiński, M. Chorev, P. Rovero, A.M. Papini, R. Latajka, Design, synthesis and conformational studies of clicked oxytocin analogs, 63rd Annual Congress of Polish Chemical Society, 13-17.09.2021, Łódź, Poland
  6. A. Staśkiewicz, L. Macchia, F. Nuti, M. Jewgiński, M. Chorev, P. Rovero, A.M. Papini, R. Latajka, Design and synthesis of clicked oxytocin analogs, 25th Polish Peptide Symposium, 08 12.09.2019, Wojanów, Poland.
  7. A. Kluczyk, T. Olszewski, N. Zuzak, W. Pietrowicz, A. Staśkiewicz, A. Dambinova, R. Bąchor, B. Setner, M. Kijewska, P. Stefanowicz, Z. Szewczuk, Od wymiany wodór-deuter do reakcji Wittiga na nośniku stałym: fosfobetainowe koniugaty peptydowe, 60. Zjazd Naukowy Polskiego Towarzystwa Chemicznego, 17 21.09.2017, Wrocław, Poland.

Publications

  1. A. Staśkiewicz, M. Quagliata, F. Real Fernandez, F. Nuti, R. Lanzillo, V. Brescia-Morra, H. Rusche, M. Jewginski, A. Carotenuto, D. Brancaccio, R. Aharoni, R. Arnon, R. Rovero, R. Latajka, A.M. Papini, Role of Helical Structure in MBP Immunodominant Peptides for Efficient IgM Antibody Recognition in Multiple Sclerosis, Front. Chem., 2022, 10, 885180, 1-11. DOI: 10.3389/fchem.2022.885180.
  2. P. Ledwoń, A. Staśkiewicz, M. Jewgiński, R. Latajka, Peptidomimetics and aromatic foldamers in biological chemistry, Wiadomości Chemiczne, 2022, 76, 5-6, 349-363, DOI: 10.53584/wiadchem.2022.5.6.
  3. A. Staśkiewicz, P. Ledwoń, P. Rovero, A.M. Papini, R. Latajka, Triazole-modified peptidomimetics: an opportunity for drug discovery and development, Front. Chem., 2021, 9, 674705, 1-16. DOI: 10.3389/fchem.2021.674705.
  4. An Optimised Di-Boronate-ChemMatrix Affnity Chromatography to Trap Deoxyfructosylated Peptides as Biomarkers of Glycation, M. Kijewska, F. Nuti, M. Wierzbicka, M. Waliczek, P. Ledwoń, A. Staśkiewicz, F. Real-Fernandez, G. Sabatino, P. Rovero, P. Stefanowicz, Z. Szewczuk, A.M. Papini, 2020, Molecules, vol. 25, nr 3, art. 755, str. 1-15.
  5. Wpływ reszt ΔPhe na konformację łańcucha peptydowego, P. Ledwoń, A. Staśkiewicz, M. Jewgiński, R. Latajka, 2020, Wiadomości Chemiczne, vol. 74, nr 1-2, str. 9-32.
  6. Wpływ różnych reszt β-aminokwasowych na zdolności koordynacyjne peptydów wobec jonów metali przejściowych, J.I. Krzciuk Gula, P. Ledwoń, A. Staśkiewicz, R. Latajka, 2020, Wiadomości Chemiczne, vol. 74, nr 3-4, str. 285-310.