Ewa Grela

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Born: 11.01.1990, Brzeg.

Hobby: Japanese language and culture, fantasy books.

Email: ewa.grela@pwr.edu.pl



Education

2013 – present – PhD studies in Department of Bioorganic Chemistry, Wrocław University of Technology

Supervisor: prof. Paweł Kafarski


2013 – MSc in Pharmaceutical Biotechnology, Department of Chemistry, Wrocław University of Technology

Supervisor: dr Agnieszka Grabowiecka

Master's thesis: "Bactericidal and bacteriostatic activity of novel biologically active aminophosphonates"




Publications

1. K. Macegoniuk, E. Grela, J. Palus, E. Rudzińska-Szostak, A. Grabowiecka, M. Biernat, Ł. Berlicki; 1,2-Benzisoselenazol-3(2H)‑one derivatives as a new class of bacterial urease inhibitors; Journal of Medicinal Chemistry; 2016, 59: 8125-8133.

2. E. Grela, A. Dziełak, K. Szydłowska, A. Mucha, P. Kafarski, A. Grabowiecka; Whole-cell Proteus mirabilis urease inhibition by aminophosphinates for the control of struvite formation; Journal of Medical Microbiology; 2016, 65: 1123-1129.

3. E. Grela, A. Ząbek, A. Grabowiecka; Interferences in the optimization of the MTT assay for viability estimation of Proteus mirabilis; Avicenna Journal of Medical Biotechnology; 2015, 7(4): 159-167.

4. E. Grela, A. Grabowiecka; Znaczenie inhibitorów ureolizy w nowoczesnym rolnictwie; Przemysł Chemiczny; 2015, 94(11): 1990-1994.

5. E. Grela; Proteus mirabilis as the example of ureolytic pathogen: Characteristics and methodology; Na pograniczu chemii i biologii; Volume XXXIII, UAM Poznań 2014, P. 305-311.


Patent applications

1. A. Grabowiecka, Ł. Berlicki, A. Mucha, K. Macegoniuk, E. Grela, P. Kafarski; Zastosowanie pochodnych kwasu aminometylofosfinowego; Polish Patent Application, P.407413, 06.03.2014.

2. A. Grabowiecka, Ł. Berlicki, A. Mucha, K. Macegoniuk, E. Grela, P. Kafarski; Pochodne kwasu aminometylofosfinowego, sposób ich wytwarzania oraz zastosowanie; Polish Patent Application, P.407412, 06.03.2014.


Conference communications

1. Poster: E. Grela, A. Grabowiecka; Aminophosphinic urease inhibitors as permeabilizers; 10th Parnas Conference; Wrocław, Poland, 10-12.07.2016.

2. Oral presentation: E. Grela, M. Biernat, A. Grabowiecka; Novel aminophosphinates as a factor limiting the ureolytic activity of Helicobacter pylori; 12th European Workshop on Phosphorus Chemistry; Kassel, Germany, 16-18.03.2015.

3. Poster: K. Macegoniuk, E. Grela, A. Grabowiecka, Ł. Berlicki; Bis(aminomethyl)phosphinic acids as inhibitors of intracellular Helicobacter pylori urease; 12th European Workshop on Phosphorus Chemistry. Kassel, Germany, 16-18.03.2015.

4. Oral presentation: E. Grela; Proteus mirabilis as the example of ureolytic pathogen: Characteristics and methodology; XII Ogólnopolskie Seminarium Doktorantów "Na pograniczu chemii i biologii"; Karpacz, Poland, 21-24.05.2014.

5. Poster: A. Grabowiecka, Ł. Berlicki, E. Grela, P. Kafarski; N-Substituted aminophosphonic and aminophosphinic acids for the control of ureolytic pathogens; 22TH Polish Peptide Symposium, Kudowa Zdrój, Poland, 01-05.09.2013.