Ewa Rudzińska-Szostak

From Bioorganic
Jump to: navigation, search
Rudzinska.jpg

Born: Opole, Poland, June 15, 1975.

Education:

2000 - MSc - Department of Ecological Chemistry, Institute of Chemistry, University of Opole.

2004 - Ph.D. - Institute of Organic Chemistry, Biochemistry and Biotechnology, Wrocław University of Technology.

E-mail: ewa.rudzinska@pwr.wroc.pl

Adress:

Department of Bioorganic Chemistry

Wroclaw University of Technology

Wybrzeze Wyspianskiego 27, 50-370 Wroclaw, Poland.

Phone: (48-71) 3202952


Research interests

  • Enantioseparation of organic compounds by different analytical methods (particulary: capillary electrophoresis, high performance liquid chromatography, nuclear magnetic resonance spectroscopy).
  • Ligand-receptor interactions analysis using nuclear magnetic resonace techniques.
  • Design of molecular receptors interacting with compounds bearing different functional group.


Foreign training period

2000 - Department of Analytical Chemistry, Lund University, Prof. Jan Ake Jonnson, Supported liquid membrane extraction of peptides using Aliquat 336 as a carrier, ( 3 month)


Awards

2005 Rector of Wrocław Uniwersuty of Technology Award for doctoral dissertation

Publications

  1. Szefczyk, M.; Węglarz-Tomczak, E.; Fortuna, P.; Krzysztoń, A.; Rudzińska-Szostak, E.; Berlicki, Ł., Controlling the Helix Handedness of ααβ-Peptide Foldamers through Sequence Shifting Angew. Chem. Int. Ed. 2017, 56, 2087. View at Publisher
  2. Rudzińska-Szostak, E.; Berlicki, Ł., Sequence engineering to control the helix handedness of peptide foldamers Chem. Eur. J. 2017, accepted.
  3. Macegoniuk, K.; Grela, E.; Palus, J.; Rudzińska-Szostak, E.; Grabowiecka, A.; Biernat, M.; Berlicki, Ł., 1,2-Benzisoselenazol-3(2H)-one Derivatives As a New Class of Bacterial Urease Inhibitors. J. Med. Chem. 2016, 59, 8125. View at Publisher
  4. Rudzińska-Szostak, E.; Górecki, Ł. Berlicki, Ł.; Ślepokura, K.; Mucha, A., Zwitterionic Phosphorylated Quinines as Chiral Solvating Agents for NMR Spectroscopy Chirality 2015, 27, 752. View at Publisher
  5. Górecki, Ł.; Berlicki, Ł.; Mucha, A.; Kafarski, P.; Ślepokura, K.; Rudzińska-Szostak, E., Phosphorylation as a Method of Tuning the Enantiodiscrimination Potency of Quinine – an NMR Study. Chirality 2012, 24, 318. View at Publisher
  6. Katarzyńska, J.; Mazur, A.; Rudzińska, E.; Artym, J.; Zimecki, M.; Jankowski, S.; Zabrocki, J., Cyclolinopeptide derivatives modify methotrexate-induced suppression of the humoral immune response in mice. Eur. J. Med. Chem. 2011, 46, 4608. View at Publisher
  7. Rudzińska, E.; Dziędzioła, G.; Berlicki, Ł.; Kafarski, P., Enantiodifferentiation of alpha–Hydroxyalkanephosphonic Acids in 31P NMR with Application of alpha–Cyclodextrin as Chiral Discriminating Agent. Chirality 2010, 22, 63. View at Publisher
  8. Rudzińska, E.; Berlicki, Ł.; Kafarski, P.; Lammerhofer, M.; Mucha, A., Cinchona alkaloids as privileged chiral solvating agents for enantiodiscrimination of N-protected aminoalkanephosphonates - a comparative NMR study. Tetrahedron Asymmetry 2009, 20, 2709. View at Publisher
  9. Rudzińska, E.; Poliwoda, A.; Berlicki, Ł.; Mucha, A.; Dżygiel, P.; Wieczorek, P.P.; Kafarski, P., Enantiodifferentiation of N-benzyloxycarbonylaminophosphonic and phosphinic acids and their esters using cyclodextrins by means of capillary electrophoresis. J. Chromat. A 2007, 1138, 284. View at Publisher
  10. Rudzińska, E.; Berlicki, Ł.; Mucha, A.; Kafarski, P., Analysis of pD Dependent Complexation of N-Benzyloxycarbonylaminophosphonic Acids by a-Cyclodextrin. Enantiodifferentation of Phosphonic Acid pKa V alues Chirality 2007, 19, 764. View at Publisher
  11. Młynarz, P.; Rudzińska, E.; Berlicki, Ł.; Kafarski, P., Organophosphorus supramolecular chemistry. Part 2. Organophosphorus receptors Curr. Org. Chem. 2007, 11, 1593.
  12. Rudzińska, E.; Berlicki, Ł.; Mucha, A.; Kafarski, P., Chiral discrimination of ethyl and phenyl N-benzyloxycarbonylaminophosphonates by cyclodextrins. Tetrahedron Asymmetry 2007, 18, 1579. View at Publisher
  13. Berlicki, Ł.; Rudzińska, E.; Młynarz, P.; Kafarski, P., Organophosphorus supramolecular chemistry. Part 1. Receptors for organophosphorus compounds. Curr. Org. Chem. 2006, 10, 2285.
  14. Berlicki, Ł.; Rudzińska, E.; Mucha, A.; Kafarski, P., Cyclodextrins as NMR probes in the study of the enantiomeric compositions of N-benzyloxycarbonylamino-phosphonic and phosphinic acids. Tetrahedron-Asymmetry 2004, 15, 1597. View at Publisher
  15. Berlicki, Ł.; Rudzińska, E.; Kafarski, P., Enantiodifferentiation of aminophosphonic and aminophosphinic acids with alpha- and beta-cyclodextrins. Tetrahedron-Asymmetry 2003, 14, 1535. View at Publisher
  16. Rudzinska, E.; Wieczorek, P.; Kafarski, P., Separation of aminoalkanephosphonic acid enantiomers by indirect UV detection capillary electrophoresis with application of cyclodextrins. Electrophoresis 2003, 24, 2693. View at Publisher
  17. Rudzinska, E., Zastosowanie elektroforezy kapilarnej do analizy związków optycznie czynnych. Na pograniczu chemii i biologii, Wydawnictwo UAM, Poznań 2003, 9, 199.
  18. Rudzinska, E.; Dzygiel, P.; Wieczorek, P.; Kafarski, P., Separation of aromatic aminophosphonic acid enantiomers by capillary electrophoresis with the application of cyclodextrins J. Chromatogr. A 2002, 979, 115.
  19. Dzygiel, P.; Rudzinska, E.; Wieczorek, P.; Kafarski, P., Determination of optical purity of phosphonic acid analogues of aromatic amino acids by capillary electrophoresis with alpha-cyclodextrin. J. Chromatogr. A 2000, 895, 301.