Katarzyna Groborz

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Born: 04.04.1992, Cieszyn

Hobby: herpetology, classical music

e-mail: katarzyna.groborz@pwr.wroc.pl

Phone: (+48) 71 320 2455


Master of Science, 2016, Wroclaw University of Technology, Poland, “Substrate specificity profiling of Cathepsin G S3’pocket using natural and unnatural amino acids.”, supervisor: prof. Marcin Drag


  1. Poreba M, Rut W, Vizovisek M, Groborz K, Kasperkiewicz P, Finlay D, Vuori K, Turk D, Turk B, Salvesen GS, Drag M, Selective imaging of cathepsin L in breast cancer by fluorescent activity-based probes Chemical Science 2018, 1. View at Publisher
  2. Gonzalez-Ramirez ML*, Poreba M*, Snipas SJ, Groborz K, Drag M, Salvesen GS (* equal contribution), Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1 Journal of Biological Chemistry 2018, 1. View at Publisher
  3. Kasperkiewicz P, Poreba M, Groborz K, Drag M, Emerging challenges in the design of selective protease substrates, inhibitors and activity-based probes for indistinguishable proteases FEBS Journal 2017, 284, 1518. View at Publisher
  4. Rut, W.; Kasperkiewicz, P.; Byzia, A.; Poreba, M.; Groborz, K.; Drag, M., Recent advances and concepts in substrate specificity determination of proteases using tailored libraries of fluorogenic substrates with unnatural amino acids Biol. Chem. 2015, 396, 329. View at Publisher

Awards and honours

2015 December Scholarship of the Ministry of Science and Higher Education for scientific achievements

Conference Communications

  1. K. Groborz, P. Kasperkiewicz, M. Drąg, Unnatural Amino Acids In Design of Proteases Probes, Chemical Probes: Exploring Avenues for Protein Investigation, Łodz, Poland, 25-26.04.2016 (oral presentation)
  2. M. Poreba, K. Groborz, M. Navarro, S. J. Snipas, M. Drag, G. Salvesen, A TRAIL/trial to monitor caspase-8 activation and processing in human T lymphocytes using tailored activity based probes., Pacific Coast Protease Spring School, Miracle Springs Resort & Spa, Desert Hot Springs, California, 24-27.04.2016 (poster)
  3. P. Kasperkiewicz, K. Groborz, M. Poreba, J. Hachmann, S. Snipas, G. Salvesen, M. Drag, MALT1 activity based probe, XVth International Symposium on Proteases, Inhibitors and Biological Control, Portorož, Slovenia, 17-21.09.2016 (poster)
  4. M. Poreba, K. Groborz, M. Drag, G. Salvesen Small molecule caspase substrates, inhibitors, and activity based probes. How far can we go?, 15th Annual SBP Postdoctoral Research Symposium, LaJolla, USA, 15.09.2016 (poster)