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Department of Bioorganic Chemistry is one of 15 departments of Faculty of Chemistry, Wrocław University of Technology. It was founded in 1971 by Professor Przemysław Mastalerz in response to introduction of biochemistry and biotechnology curricula at Faculty of Chemistry. Now it is headed by Professor Paweł Kafarski and formed by 6 professors, 10 assistant professors and over 25 PhD students doing research on a border of chemistry and biology.


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Recent papers

Nanosilica synthesis mediated by Aspergillus parasiticus strain.
Pieła A, Żymańczyk-Duda E, Brzezińska-Rodak M, Duda M, Grzesiak J, Klimek-Ochab M
Fungal Biology 2018, 1
DOI: 10.1016/j.funbio.2018.02.004

Recent papers

Unique Substrate Specificity of SplE Serine Protease from Staphylococcus aureus
Stach N, Kalinska M, Zdzalik M, Kitel R, Karim A, Serwin K, Rut W, Larsen K, Jabaiah A, Firlej M, Wladyka B, Daugherty P, Stennicke H, Drag M, Potempa J, Dubin G
Structure 2018, 1
DOI: 10.1016/j.str.2018.02.008

Recent papers

Fungal synthesis of chiral phosphonic synthetic platform – Scope and limitations of the method
Serafin-Lewańczuk M, Klimek-Ochab M,Brzezińska-Rodak M, Żymańczyk-Duda E
Bioorganic Chemistry 2018, 77, 402
DOI: 10.1016/j.bioorg.2018.01.027

Recent papers

Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1
Gonzalez-Ramirez ML*, Poreba M*, Snipas SJ, Groborz K, Drag M, Salvesen GS (* equal contribution)
Journal of Biological Chemistry 2018, 1
DOI: 10.1074/jbc.RA117.001329

Recent papers

Selective imaging of cathepsin L in breast cancer by fluorescent activity-based probes
Poreba M, Rut W, Vizovisek M, Groborz K, Kasperkiewicz P, Finlay D, Vuori K, Turk D, Turk B, Salvesen GS, Drag M
Chemical Science 2018, 1
DOI: 10.1039/c7sc04303a

Recent papers

Yeast as a versatile tool in biotechnology.
Żymańczyk-Duda Ewa, Brzezińska-Rodak Małgorzata, Klimek-Ochab Magdalena, Duda Maciej, Zerka Agata
Yeast - industrial applications / ed. by Antonio Morata and Iris Loira. Rijeka 2017, 1, 3

Recent papers

Rapid enantiodifferentation of chiral organophosphorus compounds by 31P NMR spectroscopy in the presence of α-cyclodextrin as the chiral solvating agent
Kmiecik Natalia, Monika Serafin, Tomasz Olszewski, Żymańczyk-Duda Ewa
Spectroscopy 2017, 32, 1

Recent papers

Bioconversion of aminophosphonates to hydroxyphosphonates via two step redox reactions employing fungi
Kmiecik Natalia, Majewska Paulina, Kozyra Kinga M, Żymańczyk-Duda Ewa
Phosphorus, Sulfur, and Silicon and the Related Elements 2017, 1, 1

Recent papers

Biokatalityczny sposób otrzymywania (S)-2-hydroksy-2-fenyloetanofosfonianu dietylu
Górak Monika, Żymańczyk-Duda Ewa
Patent 2017, 408430, 1

Recent papers

Nanokrzemionka - bioperspektywa i potencjał przemysłowy. Cz. 2.
Fajfer, D.; Zielonka, A.; Klimek-Ochab, M.
Laboratorium-Przegląd Ogólnopolski 2017, 32